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A trans-institutional team of researchers at Vanderbilt University Medical Center and Vanderbilt University has received an $11 million Cancer Moonshot grant to build a single-cell resolution atlas to map out the routes that benign colonic polyps take to progress to colorectal cancer, the third most common cancer among both men and women in the United States.

A new study by Harvey Murff finds that diabetics who take metformin have lower rates of liver cancer than those who take other diabetes drugs.

Stephen Deppen and colleagues have developed an updated map showing new areas of increased risk for a common lung infection.

Research led by Matthew Tyska gives new insight into the formation of the lining of the gut that helps us absorb nutrients and guard against illness.

Researchers led by melanoma researcher Douglas Johnson have answered questions about the incidence and timing of rare but sometimes fatal reactions to the most widely prescribed class of immunotherapies.

An immune cell called CD8+ is supposed to attack disease, but it can also contribute to inflammation, which can lead to insulin resistance and type 2 diabetes.

Kasey Vickers has developed a new analytical method for to study small RNAs, a poorly understood component of the genome.

New research by an international team that includes Vanderbilt researchers shows how a common diabetes drug blocks glucose production by the liver, suggesting new avenues for treatment.

A Vanderbilt University Medical Center pilot study of treating late-life depression in nonsmokers with transdermal nicotine (nicotine patch) has yielded some promising results, but the study’s author cautions that more study is needed.

There’s promise in specific immune system peptides—amino acid compounds that signal cells how to function. In this case, they may be affecting brain activity and, by extension, drug cravings. Read More

The discovery of these antibodies could significantly improve the diagnosis and treatment of the leading cause of stomach illness in the world.

The discovery that high levels of bile acids appear to blunt cravings for cocaine could lead to new treatments for addiction.

A symptom related to hypertension may play a role in cognitive decline, according to new research by Angela Jefferson.

Vanderbilt researchers have discovered new insights into the treatment of chronic graft-versus-host-disease, a complication of bone marrow and stem cell transplants.

James Galligan and Lawrence Marnett have discovered a new histone modification that can affect gene expression.

A newly discovered role for the "Sonic the Hedgehog" protein in the proper development of the cerebellum.

New research by Masoud Ghamari-Langroudi and colleagues has revealed that a certain brain protein called MC3R plays a role in causing the body to reset its "ideal" weight.

People who qualify for both Medicaid and Medicare tend to have very serious, complex health problems, but new research by Laura Keohane shows that their rate of healthcare spending is not rising any faster than that of people eligible for just Medicare.

Modern statistical tools are not very accurate when it comes to predicting the discrete and non-symmetric behaviors of individual cells. Gregor Neuert and colleagues say that's because the wrong tools are being used.

ianchun Chen, Raymond Harris and colleagues have identified a potential new target for treating acute kidney injury.