Health And Medicine
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Pathology of septic shock
The signaling molecule IL-15 promotes septic shock, a life-threatening condition involving organ injury caused by infection. Read MoreFeb 8, 2017
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Dementia linked to diet
Some memory deficits observed in Alzheimer鈥檚 disease may be due to co-morbid illnesses 鈥 not the disease itself 鈥 and may be reversed by lifestyle changes or pharmacologic interventions. Read MoreFeb 7, 2017
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Bacterial signaling systems
Vanderbilt researchers have identified a unique example of communication between bacterial signaling systems, which may have relevance for antibiotic resistance. Read MoreFeb 3, 2017
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New target for chronic infection
An enzyme in macrophage immune cells may be a good target for treating chronic infections, Vanderbilt researchers have discovered. Read MoreFeb 2, 2017
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Gene mutation discovery may hold autism clues:鈥坰tudy
Researchers at Vanderbilt have identified what may be a genetic 鈥渟moking gun鈥 for autism spectrum disorder (ASD) 鈥 a mutation in the gene for the critical neuronal protein CaMKII. Read MoreFeb 2, 2017
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New Physician Science Doctoral Program graduates first student
As a fellow in pulmonary and critical care medicine at Vanderbilt University School of Medicine, Bradley Richmond, M.D., saw a lot of patients with chronic obstructive pulmonary disease (COPD), an inflammatory lung disease caused most often by long-term exposure to cigarette smoke. Read MoreFeb 2, 2017
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Studies find tonsillectomies offer only modest benefits
Removing tonsils modestly reduced throat infections in the short term in children with moderate obstructive sleep-disordered breathing or recurrent throat infections, according to a systematic review conducted by the Vanderbilt Evidence-based Practice Center for the Agency for Healthcare Research and Quality (AHRQ). Read MoreJan 26, 2017
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Flu vaccine response in older adults
High dose flu vaccine boosts the immune response in older adults by increasing activation of certain immune cells. Read MoreJan 25, 2017
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Saliva test for obesity risk
鈥淓pigenetic signatures鈥 in DNA may present an opportunity for prevention of or early intervention in childhood obesity. Read MoreJan 24, 2017
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Improving vaccine formulations
The compound MPLA is an attractive vaccine component, designed to elicit a robust immune response. Read MoreJan 20, 2017
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Colorectal cancer clues
Although cancers arising from different areas of the large intestine are heterogeneous, they appear to use similar important tumorigenic pathways. Read MoreJan 19, 2017
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Surprising finding by VU鈥坱eam sheds light on fibrotic disease
Integrins are membrane proteins made up of combinations of different 鈥渁lpha鈥 and 鈥渂eta鈥 subunits that enable cells throughout the body to interact with their surroundings. Read MoreJan 19, 2017
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Metastatic pancreatic cancer 鈥榬eprograms鈥 for malignancy
Metastatic pancreatic cancer 鈥 cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths 鈥 changes its metabolism and is 鈥渞eprogrammed鈥 for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics. Read MoreJan 19, 2017
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GRE may be poor predictor of science success:鈥坰tudy
Since it was created in 1949, the Graduate Record Exam (GRE) has been one of the most widely used requirements for admission to U.S. graduate schools. As a predictor of performance and success in graduate school, however, the exam is not without its critics. Read MoreJan 19, 2017
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Amount of daylight may impact serotonin programming
The duration of exposure to daylight, or the 鈥減hotoperiod,鈥 may affect development of seasonal affective disorder by programming serotonin neurons in the brain, according to Vanderbilt University researchers. Read MoreJan 19, 2017
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A heart-brain connection
Cognitive and attention deficits observed in children following surgery before age 5 to repair congenital heart defects likely will persist into their teens and young adulthood. Read MoreJan 17, 2017
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Team鈥檚 discovery offers new insight on lung cancer risk
Researchers in the Schools of Medicine and Engineering at Vanderbilt University have discovered a proteomic 鈥渟ignature鈥 from the airways of heavy smokers that could lead to better risk assessment and perhaps new ways to stop lung cancer before it starts. Read MoreJan 12, 2017
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Investigators apply game theory to study of genomic privacy
It comes down to privacy 鈥 biomedical research can鈥檛 proceed without human genomic data sharing, and genomic data sharing can鈥檛 proceed without some reasonable level of assurance that de-identified data from patients and other research participants will stay de-identified after they鈥檙e released for research. Read MoreJan 12, 2017
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Vanderbilt-led study finds parent鈥檚 physical activity associated with preschooler activity in underserved populations
Preschool-age children from low-income families are more likely to be physically active if parents increase activity and reduce sedentary behavior while wearing movement monitors (accelerometers), according to a Vanderbilt study published today in the American Journal of Preventive Medicine. Read MoreJan 10, 2017
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Paper or screen, which is better?
To improve medical management of crisis situations, clinicians should be trained to use cognitive aids 鈥 checklists and concise manuals. Read MoreJan 10, 2017