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Vsevolod Gurevich and colleagues have discovered new insights into arrestin proteins, which turn off a cell's environmental message "inbox."

Austin Kirschner and colleagues are learning more about how the cancer drug enzalutamide combines with radiation therapy to treat difficult prostate tumors.

A commonly used muscle relaxant can cause severely low blood pressure in patients already taking a CYP1A2 inhibitor, such as ciprofloxacin, find Cecilia Chung and colleagues.

Jonathan Soslow and colleagues have found more clues to why people with Duchenne muscular dystrophy are at risk for a certain kind of heart problem.

Stephen Fesik and colleagues have uncovered more details about how a crucial component of RAS proteins, which trigger about a third of all tumors, work. This finding will help advance the discovery of new cancer therapies.

A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach cancer, Vanderbilt researchers have discovered.

VUMC has received significant grants to study pulmonary fibrosis, a progressive and irreversible disease characterized by shortness of breath and a dry cough.

Jason McGurn and colleagues have uncovered new insights into the complex and highly coordinated endocytic trafficking mechanism, which is an essential part of many cellular processes including sodium resorption by the kidney and regulation of blood plasma sodium levels. Read More

A $3.4 million grant from the National Institute of Mental Health will fund Vanderbilt research on treatment resistance in patients with major depressive disorder and schizophrenia.

Commonly thought to be harmless, enlargement of fluid-filled in the brain have been linked to cognitive problems in older adults.

Young women with separation anxiety tend to over-rely on external cues to define themselves, which can make them vulnerable to internalizing unhealthy body ideals. Read More

Vanderbilt researchers are on a quest to develop early biomarkers of treatment outcomes for patients with temporal lobe epilepsy based on their individual brain networks.

Lauren Woodard and Matthew Wilson have discovered a way to reprogram adult human kidney cells into cells similar to those that form during embryonic development, which could lead to new kidney disease treatments.

Though neurological activity is generally associated with the brain's gray matter, Muwei Li and colleagues have now measured it in white matter as well.

New research into the enzyme topoisomerase II sheds light on how it helps DNA replicate properly. Read More

Stimulating the vagus nerve triggers certain epigenetic changes involving learning and memory. Read More

Normal brain aging patterns in patients with a psychotic disorder occur at an accelerated rate, impacting the patient’s cognitive functioning and suggesting treatment intervention in the early psychosis period may improve long-term outcomes.

Heidi Hamm and colleagues have reported the first animal model of a "shut-off valve" for neurotransmitter and hormone release through SNARE complex-mediated membrane fusion.

David Cortez and colleagues have discovered a new DNA repair mechanism.

A team of Vanderbilt researchers mapped out the genomic landscape of a metastatic malignant proliferating tricholemmal tumor and identified a targeted treatment for this very rare cancer.